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Message
re: Tylenol beat Trump by eight years.
Posted on 9/24/25 at 12:34 pm to HouseMom
Posted on 9/24/25 at 12:34 pm to HouseMom
quote:
There are a lot of them already. Clearly there is a reason for so many studies, but the problem is that they can establish a link but not causation.
And color me skeptical, but when there's smoke, there's usually fire. There is almost nothing inherently "safe" for pregnant mothers to ingest other than food, and not even all of that...deli meat, soft cheese, alcohol, etc. We weren't allowed to take Advil or Aspirin, either.
So I wouldn't be shocked at all if this turns out to be a no-no for expectant mothers or babies/toddlers. I mean, there was a point that Johnson's baby powder and thalidomide were approved, as well.
And it could wind up being something as seemingly innocuous as the coating on the tablets or the dyes in the infant formula. I always thought it was weird that they make a "dye-free" version for toddlers. Why even sell the one with the dye if it isn't harmful?
We put alllll kinds of things into our bodies (in the name of "medicine") that are basically poisons, and our bodies really don't know how to process them. The pharmaceutical companies are the modern-day mob with the influence they have over Congress.
With the Tylenol the issue has always been how much you're taking (I wouldn't be at all surprised if Tylenol is the #1 OTC medication that's taken beyond it's therapeutic dosage). But that the risk of complications from a fever during pregnancy FAR outweighs the risk of taking Tylenol as directed. And the potential risks of complications with NSAIDs are far worse as well.
Like you said, there's risk with everything during pregnancy.
This post was edited on 9/24/25 at 12:37 pm
1
Posted on 9/24/25 at 12:37 pm to HouseMom
quote:
I realize I'm contradicting myself, but it seems like a meta-analysis of previous studies determined at least a link worth taking seriously.
Just FYI that study is not technically a meta-analysis though it may look like one, it is a navigation guide systematic review.
If anyone wants to read the new study it is here:
Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology
For the last graph readers here is the conclusion emphasis mine:
quote:
Our analysis demonstrated evidence consistent with an association between exposure to acetaminophen during pregnancy and offspring with NDDs, including ASD and ADHD, though observational limitations preclude definitive causation. This analysis, using the Navigation Guide methodology, synthesizes evidence from several population studies and supports an association between prenatal acetaminophen exposure and increased NDD incidence, including ADHD, ASD, and other NDDs. While population-level trends in NDD rates have risen, potentially due to several factors including improved diagnostics and external exposures, further research is needed to confirm these associations and determine causality and mechanisms. A causal relationship is plausible because of the consistency of the results and appropriate control for bias in the large majority of the epidemiological studies, as well as acetaminophen’s biological effects on the developing fetus in experimental studies. Further, a potential causal relationship is consistent with temporal trends—as acetaminophen has become the recommended pain reliever for pregnant mothers, the rates of ADHD and ASD have increased > 20-fold over the past decades]. While this association warrants caution, untreated maternal fever and pain pose risks such as neural tube defects and preterm birth, necessitating a balanced approach. We recommend judicious acetaminophen use—lowest effective dose, shortest duration—under medical guidance, tailored to individual risk–benefit assessments, rather than a broad limitation.
Posted on 9/24/25 at 12:40 pm to BluegrassBelle
quote:
With the Tylenol the issue has always been how much you're taking (I wouldn't be at all surprised if Tylenol is the #1 OTC medication that's taken beyond it's therapeutic dosage).
Completely agree. If anything, maybe POTUS's rant will cause some sane people to pause before taking any medication unnecessarily during pregnancy. Tylenol, as we currently know, can wreck your liver. It can't be taken like candy.
Posted on 9/24/25 at 12:41 pm to Obtuse1
quote:
Just FYI that study is not technically a meta-analysis though it may look like one, it is a navigation guide systematic review.
Thank you for the correction. I skimmed the press release but had not read the original publication.
Posted on 9/24/25 at 12:44 pm to HouseMom
quote:
Completely agree. If anything, maybe POTUS's rant will cause some sane people to pause before taking any medication unnecessarily during pregnancy. Tylenol, as we currently know, can wreck your liver. It can't be taken like candy.
Eh, I just hope folks rely on their physicians instead of politicians for medical advice at the end of the day.
Posted on 9/24/25 at 12:51 pm to Obtuse1
quote:
Results We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis.
The last 4 studies were probably sponsored by Tylenol lol.
Posted on 9/24/25 at 12:53 pm to HouseMom
the problem is that even in that study, most of those studies were self report studies, which are known to have very suspect data
Posted on 9/24/25 at 12:55 pm to Salmon
Either way, it's enough for researchers to go back to the drawing board and formulate a controlled study (as much as possible) to finally put this to rest.
Posted on 9/24/25 at 12:57 pm to HouseMom
quote:
formulate a controlled study (as much as possible) to finally put this to rest.
I wouldn't get my hopes up
Posted on 9/24/25 at 1:03 pm to Salmon
As I said earlier, when I saw someone posted there was 20-30% increase in instance of autism in infants exposed to Tylenol that astounded me. I’d never seen or heard of any connection. And that was on top of the Tweet from Tylenol saying they’d never studied the use of their drug during pregnancy.
I’m about as far from an expert on autism, pregnancy, and Tylenol as you can get. And unlike some in this thread, I’m not going to pretend to know shite from Shineola on the matter. I was simply giving my option based on what little I’d read in the previous minutes.
And if there are studies on the matter, I’d like to know where that 20-30% number came from.
I’m about as far from an expert on autism, pregnancy, and Tylenol as you can get. And unlike some in this thread, I’m not going to pretend to know shite from Shineola on the matter. I was simply giving my option based on what little I’d read in the previous minutes.
And if there are studies on the matter, I’d like to know where that 20-30% number came from.
Posted on 9/24/25 at 1:06 pm to Darth_Vader
ok Darth
I don't think any of my posts to you were combative in any way, so not sure why that was directed at me
I don't think any of my posts to you were combative in any way, so not sure why that was directed at me
Posted on 9/24/25 at 1:08 pm to Evil Little Thing
quote:also if ur rtarded you have an increased risk of rtarded kids.
Since I was late 30s while pregnant and my husband is also old (all correlated with higher autism rates), I read anything I could about increased risk factors. Having a fever while pregnant was another association for increased risk.
I learnt the hard way. I’m 2 for 3 me
Posted on 9/24/25 at 1:08 pm to HouseMom
quote:
The last 4 studies were probably sponsored by Tylenol lol.
The study has nifty little colored graphs that express risk of bias, including financial interest, which are low (the lowest level) for the ASD studies.
Posted on 9/24/25 at 1:08 pm to Darth_Vader
quote:
If that’s true and Tylenol said in 2019 they’ve not tested their drug to be used during pregnancy, I have to ask what everyone who’s categorically stating Tylenol is safe during pregnancy is basing their assertion on?
Just because J&J nor Kenvue has ever done specific testing, it doesn't mean extensive testing on the subject hasn't been done. The fact that the study they cited is a navigation guide systematic review of many studies is an indication of the extensive testing that has been done.
One thing to note about the Tweet in the OP is it is not a post but a reply. The query has been deleted, as many questions posed to businesses are when there is a reply. The query would help with the context. There is a very high probability that the person asks if it was safe to take Tylenol when pregnant, the we do not recommend reply is perfectly warranted and probably does not read within the context like many are reading it. They simply can't and won't recommend the use of Tylenol when pregnant without full knowledge. The packaging has always referred pregnant or breastfeeding women to their doctor or healthcare professional. This is simply because they have not tested it independently (smart from a legal POV), but even if they had, they couldn't make blanket recommendations for pregnant women. To make a recommendation to not take or to take along with dose and frequency, a doctor has to have the mother's history, the pregnancy history and current labs. With this, they can together make a reasonable cost-benefit analysis.
Posted on 9/24/25 at 1:11 pm to Darth_Vader
quote:
Darth_Vader
You know you’re a real idiot when you make pride seem like a logical and sane poster
Posted on 9/24/25 at 1:17 pm to Darth_Vader
quote:Yet still lower than not treating prenatal fever, and still lower than side effects of the alternative fever reducers to the baby during pregnancy.
20-30% increase is not insignificant. In fact, it’s downright alarming.
1.2% to 1.4 or 1.5% is what the jump is based off the most recent data. Which is still lower than the chance of a miscarriage or preterm labor if a fever of 100+ is left untreated in a pregnant mother.
20-30% is a big increase, but it's a big increase of a small number.
Posted on 9/24/25 at 1:20 pm to Salmon
quote:
I don't think any of my posts to you were combative in any way, so not sure why that was directed at me
I’m sorry, I wasn’t directing that at you. You’ve been nothing but civil.
Posted on 9/24/25 at 1:26 pm to Mingo Was His NameO
quote:
Mingo Was His NameO
I think we should study whatever your mother did while pregnant with you that made you turn out to be such a miserable 4’7” tall stack of dog shite.
Posted on 9/24/25 at 1:26 pm to Darth_Vader
(no message)
This post was edited on 9/24/25 at 1:27 pm
Posted on 9/24/25 at 1:27 pm to Darth_Vader
quote:
4’7” tall stack of dog shite.
Oxymoron, do you know what that is?
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