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Started By
Message
On Testosterone and levels have spiked
Posted on 2/15/26 at 5:53 am
Posted on 2/15/26 at 5:53 am
49 year old male. History of lowish sex drive and fatigue. Went to a functional medicine doctor and got my labs in November.
Test 574 ng/dl
Free 75 pg/ml
Started on .3 ml twice a week on December 18. Took labs Feb 6 before my shot.
Test 1288 ng/dl
Free 176.6 pg/ml
My estradiol is slightly elevated at 54
Also taking boron and DHEA.
Have not consulted my doctor yet but those are both considered high. I have no nipple tenderness, sex lite has been terrific, no mood swings, and I have been working out every day. I know a lot of you guys are on test so wanted the advice here before I hit up my doc.
Test 574 ng/dl
Free 75 pg/ml
Started on .3 ml twice a week on December 18. Took labs Feb 6 before my shot.
Test 1288 ng/dl
Free 176.6 pg/ml
My estradiol is slightly elevated at 54
Also taking boron and DHEA.
Have not consulted my doctor yet but those are both considered high. I have no nipple tenderness, sex lite has been terrific, no mood swings, and I have been working out every day. I know a lot of you guys are on test so wanted the advice here before I hit up my doc.
This post was edited on 2/15/26 at 5:57 am
8
Posted on 2/15/26 at 6:09 am to Boss
Those numbers look fantastic , nothing to worry about if you are feeling good. Don't chase numbers. I feel best with my e2 in the 50s-60s , but everyone is different. I see no reason for concern here. Just my 2 cents.
Posted on 2/15/26 at 6:40 am to Boss
Welcome to the party! Your doctor should treat the symptoms and not a number. My estradiol elevates sometimes around where your at but I don’t feel any negative affects. As long as your other markers are good I’d keep on keeping on like you are.
Posted on 2/15/26 at 7:56 am to Boss
As others have said symptoms matter not numbers. Also curious why you would be on dhea when on actual testosterone?
Posted on 2/15/26 at 9:48 am to ronricks
My E2 went up to 52 but I lowed my dose to .3 (30 units) from .4 (40) and within a few weeks it was 34.
Posted on 2/15/26 at 12:38 pm to Boss
If you feel fine, no worries.
Mine has said as long as my number comes back readable and I feel ok, then there are no issues.
For reference anything over 1500 is unreadable for the lab they use.
My last check up came back at 1450 and they were ok with it
Mine has said as long as my number comes back readable and I feel ok, then there are no issues.
For reference anything over 1500 is unreadable for the lab they use.
My last check up came back at 1450 and they were ok with it
Posted on 2/16/26 at 2:24 pm to Boss
Unless you like needles, I'd go with .6 every six days which is right at the half life of most T protocols. Those numbers will settle down to the 800's in short time, but as stated above, it's about how you feel and knowing your body.
Keep an eye on PSA numbers and Hematocrit %. If Hema percent gets in the upper 50's donate blood (which is a good thing to do regardless). Enjoy feeling good again!
Keep an eye on PSA numbers and Hematocrit %. If Hema percent gets in the upper 50's donate blood (which is a good thing to do regardless). Enjoy feeling good again!
Posted on 2/16/26 at 5:35 pm to Boss
wouldn't worry about it: my total T is >1500 and E2 is 47.8 as of most recent 2 or 3 labs and my doc - one of the top HRT docs in the country - says I'm fine if I feel fine since all my other lab panels look good
Posted on 2/18/26 at 10:28 am to Boss
quote:
Test 574 ng/dl
Did not need T shots
quote:
Test 1288 ng/dl
Good gosh, I would be humping the furniture at that level.
Posted on 2/18/26 at 10:32 am to DarthRebel
Thanks for adding value to the thread. Go away troll.
Posted on 2/18/26 at 11:03 am to Boss
quote:
Go away troll.
Totally not a troll, jeeze Boss.
574 is well within normal range, any normal doctor is not going to say get on TRT at that level. TRT is a life commitment and insurance is not paying at 574.
1288 is fricking high and not a target to hit. Most clinics try to get you around 1000.
He is new to TRT and enjoying the high right now, especially at 1288, but that is going to come to an end and will probably return close to how he felt like before, probably slightly better, but the euphoria is going to wane with time.
At a 574 level, I would have looked to increase T in other ways instead of hopping on TRT. Eating and exercise would have been a better approach to beef up sex drive and fatigue.
OP - What was your hemocrit levels, the higher your numbers go, there is a chance of your blood thickness increasing. Thick blood is going to make you feel worse, besides the potential of a clot. Get ready to give blood every 8 weeks.
This post was edited on 2/18/26 at 11:07 am
Posted on 2/18/26 at 11:24 am to DarthRebel
Hematocrit before test was 45
Now 46.2. Well within limits and a negligible move.
I went to three different doctors before deciding to go on Testosterone. My free was low average and symptomatically I was lethargic with no sex drive. I eat fairly clean and exercise. Once I went to a functional medicine doctor, we decided that at 48 it was a good move because my testosterone isn’t going to get higher.
I’ve been on it since December 18th so this is my first lab draw post going on it. I talked with my doctor and we decided to do another draw in 4 weeks to recheck. If levels are still there we can either space to every 5 days or drop to .25 ml.
I’m not sure why you feel the need to assume how I will feel being on test. You sure as shite aren’t a doctor. Yeah it’s a lifelong commitment. But I am committed to increasing my longevity and this is one of the steps to help me get there.
Now 46.2. Well within limits and a negligible move.
I went to three different doctors before deciding to go on Testosterone. My free was low average and symptomatically I was lethargic with no sex drive. I eat fairly clean and exercise. Once I went to a functional medicine doctor, we decided that at 48 it was a good move because my testosterone isn’t going to get higher.
I’ve been on it since December 18th so this is my first lab draw post going on it. I talked with my doctor and we decided to do another draw in 4 weeks to recheck. If levels are still there we can either space to every 5 days or drop to .25 ml.
I’m not sure why you feel the need to assume how I will feel being on test. You sure as shite aren’t a doctor. Yeah it’s a lifelong commitment. But I am committed to increasing my longevity and this is one of the steps to help me get there.
Posted on 2/18/26 at 11:59 am to Boss
Apologies, did not notice you were the original poster in my response, I would have worded it directly towards you 
Sure I am coming across as an arse, but it does not mean you do not need to hear it.
No, but I have a lot of damn years on TRT. You pulled the trigger and did it, great. You need to know what you are feeling is not going to last. Will you return to what you were, probably not, but you will trend that way if you do nothing else. You are going to have to sleep, eat and exercise better or you are going to find yourself increasing your dosage over time to keep you at the preferred level, which is lower than where you are now.
After a year on it, you are going to really feel that return to where you were some. The first few months to a year are a honeymoon, but plan accordingly to put in the extra work down the road.
About 3-5 years in, the shots will start getting old. Honestly I get them done at a clinic now, because insurance pays, and it is a nice change up not doing them myself.
My estradiol spikes crazy sometimes, but I never feel a thing when it does.
The mood swings are going to happen, and you probably will be the last one to recognize it. Try to be aware in the back of you mind of that when things get sideways with the wife. Practice not saying the first thing that comes to mind.
You want to get into a blood donation cadence now, it can thicken rapidly. It is not so much a clot fear, but you will feel it. It will make you feel sluggish. Mine did not really start thickening until several months in, but since then if I go more than say 12 weeks giving blood it does thicken a good bit.
In the first year, you are going to put on muscle mass and probably drop a waist size or two if you already not a stick figure. This is going to happen regardless of the workouts you put in, after that you will regress back to fat if you do not keep it up.
Do not know what you are going to hit up doctor about? He/She would probably tell you, you did not need to be on it in the first place. My old doctor told me I was fine, even though it was low enough to be covered by insurance. GP doctors usually are not the ones to see for TRT, not their thing. My new doctor is not the one who prescribed it, so he just has it down in my chart as something I am on and we have never talked about it. Are you asking your doctor to write out a prescription for it? He might, but will not be covered by insurance.
Sure I am coming across as an arse, but it does not mean you do not need to hear it.
quote:
You sure as shite aren’t a doctor
No, but I have a lot of damn years on TRT. You pulled the trigger and did it, great. You need to know what you are feeling is not going to last. Will you return to what you were, probably not, but you will trend that way if you do nothing else. You are going to have to sleep, eat and exercise better or you are going to find yourself increasing your dosage over time to keep you at the preferred level, which is lower than where you are now.
After a year on it, you are going to really feel that return to where you were some. The first few months to a year are a honeymoon, but plan accordingly to put in the extra work down the road.
About 3-5 years in, the shots will start getting old. Honestly I get them done at a clinic now, because insurance pays, and it is a nice change up not doing them myself.
My estradiol spikes crazy sometimes, but I never feel a thing when it does.
The mood swings are going to happen, and you probably will be the last one to recognize it. Try to be aware in the back of you mind of that when things get sideways with the wife. Practice not saying the first thing that comes to mind.
You want to get into a blood donation cadence now, it can thicken rapidly. It is not so much a clot fear, but you will feel it. It will make you feel sluggish. Mine did not really start thickening until several months in, but since then if I go more than say 12 weeks giving blood it does thicken a good bit.
In the first year, you are going to put on muscle mass and probably drop a waist size or two if you already not a stick figure. This is going to happen regardless of the workouts you put in, after that you will regress back to fat if you do not keep it up.
Do not know what you are going to hit up doctor about? He/She would probably tell you, you did not need to be on it in the first place. My old doctor told me I was fine, even though it was low enough to be covered by insurance. GP doctors usually are not the ones to see for TRT, not their thing. My new doctor is not the one who prescribed it, so he just has it down in my chart as something I am on and we have never talked about it. Are you asking your doctor to write out a prescription for it? He might, but will not be covered by insurance.
Posted on 2/18/26 at 12:11 pm to DarthRebel
I am making changes though. Since being on it I’ve been in the gym 62 out of 63 days. I’ve cut down on drinking. I am eating cleaner and getting more protein.
I have 5 years of hematocrit levels and they ranged from 44-47.8. Where I’m at now falls squarely in the middle of that range. But I am getting my levels rechecked in 5 weeks to see where I am at and adjust as needed.
Functional medicine doctors use numbers as a guide but use how you are feeling also into the equation. My GP is a strict numbers guy. Again I’ve been on it for about two months now so still figuring it out.
I do have friends that are in low 50s that have been on it for years and they did not experience the regression that you are talking about. My guess is everyone reacts differently.
I have 5 years of hematocrit levels and they ranged from 44-47.8. Where I’m at now falls squarely in the middle of that range. But I am getting my levels rechecked in 5 weeks to see where I am at and adjust as needed.
Functional medicine doctors use numbers as a guide but use how you are feeling also into the equation. My GP is a strict numbers guy. Again I’ve been on it for about two months now so still figuring it out.
I do have friends that are in low 50s that have been on it for years and they did not experience the regression that you are talking about. My guess is everyone reacts differently.
Posted on 2/19/26 at 8:53 am to Boss
quote:
Test 574 ng/dl
quote:
49 year old male
Those are honestly not bad numbers for being 50...
Im sure you do feel better now with that spike but something else underlying was probably causing the fatigue
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