- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Winter Olympics
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
re: Where are we with Hydroxychloroquine?
Posted on 3/28/20 at 5:03 pm to Little Trump
Posted on 3/28/20 at 5:03 pm to Little Trump
Cuomo said this morning they’ve given it to roughly 1100 patients starting Thursday and will have results possibly tomorrow but most likely Monday.
2
Posted on 3/28/20 at 5:04 pm to timdonaghyswhistle
quote:
Actually, there is a 50% chance you will die--based on one very limited study.
What are the odds without it?
Oh, and link please.
Posted on 3/28/20 at 5:50 pm to Little Trump
This drug has got to be easy to manufacture in huge quantities. 50 years ago there were a couple hundred thousand doses taken once a week for malaria prophylaxis by men in Vietnam with little or no side effects. If it is successful when given to critically ill flu victims, what is the down side to using it for therapeutic doses in infected people with milder symptoms to prevent it getting worse? Sometimes even a placebo gives people hope.
Posted on 3/28/20 at 5:52 pm to beachdude
I thought Bayer promised millions of doses to the US.
Posted on 3/28/20 at 5:52 pm to beachdude
On Friday on Rush’s show they said Israel is sending 4 million doses to the US with 6 million more to come
Posted on 3/28/20 at 5:53 pm to rpg37
I'm not a conspiracy nut but it has been difficult to bolster the inventory of this med and azrithromycin. It is my understanding that this combo is being looked at as more of a prophylactic. To my knowledge they are not being used presently. Plus with just 80 doses who would be eligible? That's my concern. My guess would be the health care workers who are in constant contact with a COVID positive patient. The 36 patients in our hospital have been in isolation. The patients that tested positive from the drive thru testing are called and told to self isolate. Have they been doing that since they were swabbed? I doubt it.
Posted on 3/28/20 at 5:56 pm to FredsGotSlacks
quote:
by FredsGotSlacks
Cuomo said this morning they’ve given it to roughly 1100 patients starting Thursday and will have results possibly tomorrow but most likely Monday.
That straight talking democrat Cuomo would get the message out of what a success the drug is
Excellent news although I thought he was starting it there Tuesday
Posted on 3/28/20 at 5:57 pm to mtntiger
quote:
What are the odds without it?
Oh, and link please.
He is obviously referring to the couple that ingested it: the man died, the woman survived.
Hence, a 50% chance that you will die......
Posted on 3/28/20 at 6:20 pm to LSUGrrrl
quote:
I thought Bayer promised millions of doses to the US.
Bayer’s formulation isn’t approved for US usage. So there’s probably some hoops for them to jump through.
Posted on 3/28/20 at 6:30 pm to FredsGotSlacks
quote:
...starting...Thursday.
Tuesday, and it was being used in a Manhattan hospital (Lenox Hill as per Dr. William Grace) as of last Thursday, a week ago.
Posted on 3/28/20 at 6:40 pm to Little Trump
It’s very effective if taken before the patient is too far gone.
It’s not being widely publicized because:
1. Suppliers want to avoid hoarding
2. MSM doesn’t want it to work
It’s not being widely publicized because:
1. Suppliers want to avoid hoarding
2. MSM doesn’t want it to work
Posted on 3/28/20 at 7:07 pm to Mid Iowa Tiger
quote:
There are multiple studies that show >90% survival using the drug.
Let's look at some of the studies reported to date. If you have others in addition to the below I would love a link to the publication to read.
1) First French Study
open label, n=42 (26 HCQ, 16 control (SOC only)
6 of the evaluable subjects in the treatment group received azithromycin in addition to HCQ. The viral clearance in these subjects compared to the HCQ alone or control subjects was statistically significant.
Interestingly, 6 patients in the treatment group were considered "lost to follow-up", including 3 who had to be admitted to ICU for worsening disease, 1 death, 1 who discontinued treatment due to side effects, and 1 who left the hospital still PCR positive. So they basically censored those patients who got worse or had side effects. That's not good science.
Also to note these were mostly mild patients at presentation, with 16.7% asymptomatic, and 61.1% upper respiratory (that is, not yet showing signs of pneumonia, SOB, etc) These are patients that may not even be tested in the US, and would not be hospitalized.
2) Second French Study, same investigators
open label, n=80
53.8% of patients presented with LRTI symptoms and 41.2% with URTI
symptoms. Only 15% of patients were febrile. Four patients were asymptomatic carriers. The majority of patients had a low NEWS score (92%) and 53.8% of patients had LDCT compatible with pneumonia.
As above, the non-febrile patients wouldn't even be tested in most states in the US. We already know that most cases are mild cases. Without a prospective placebo controlled study we do not know the typical course of viral clearance of these patients and whether the therapy (HCQ + Azithromycin) makes any difference whatsover
What neither of these studies show is whether HCQ + Azithromycin:
- prevent progression of disease
- reduce severity of disease
- reduce need for supplemental oxygenation
- reduce need for mechanical ventilation
- shorten time on mechanical ventilation
- improve mortality rate
Posted on 3/28/20 at 7:20 pm to shell01
There is also the australian study that came right after the french study. Just saw a tweet that said New York has banned the use other than clinical trials. crazy since it has been approved for off label use 
Posted on 3/28/20 at 7:24 pm to mtntiger
quote:
What are the odds without it?
Oh, and link please.
Here you go
quote:
Sad as their predicament is, the only “advice” to be gleaned from the couple’s behavior is “don’t be a unimaginable moron.” The headline of NBC’s story is “Arizona man dies after ingesting chloroquine in an attempt to prevent coronavirus.” But this is not correct. He did not “ingest chloroquine,” and neither did his wife. Rather, he ingested chloroquine phosphate, which his wife found in her back pantry the form of fish tank cleaner. From the interview: “I was in the pantry stacking dog food and I just saw it sitting in the back shelf and thought, ‘Hey, isn’t that the stuff they’re talking about on TV?’ And it was.” It wasn’t. I’m afraid that this is the stuff of idiocracy — the equivalent of a person seeing a bucket of chlorine next to her swimming pool and drinking it because the letters on the outside are arranged in a similar order to the word “chloroquine.”
Posted on 3/28/20 at 7:25 pm to Little Trump
I've got my prescription and if I start showing signs of COVID-19 I'm damn sure taking it.
Posted on 3/28/20 at 7:42 pm to beachdude
can give you the runs but that is about it for side effects. I think these dem govs that are banning it should be told to pound sand.
Posted on 3/28/20 at 7:46 pm to beezy
quote:
There is also the australian study that came right after the french study.
Link? David Paterson from Queensland is running a trial now, but only reference to results I can find is in-vitro testing not in patients.
Listen, I hope this stuff works, and look forward to seeing results of the (better) studies currently ongoing.
And side note "Approved for off label use" is an oxymoron. It's either an approved (labeled) indication, or not (off-label).
Posted on 3/28/20 at 8:00 pm to ItalianTiger
quote:
Only 80 doses at our hospital. As of last night we had a total of 36 COVID pos patients. Waiting on 40 more test results from LSU. Don't know if the medication is being used.
Last week the Head of Immunology at LSU-NOLA said on Laura Ingraham that they were using it on Patients with risk factors and patients with symptoms. They were using remdesivir on the worst off patients I believe. If you were infected but not in any big health risk they were not giving either of these drugs.
Fox News video
This post was edited on 3/28/20 at 8:04 pm
Posted on 3/28/20 at 8:31 pm to shell01
quote:
Link? David Paterson from Queensland is running a trial now, but only reference to results I can find is in-vitro testing not in patients.
in-vitro
secret study
based on the first article, even though it mentions test tubes, i totally believe they were treating patients. the article is kinda vague in that regard. the second article reinforces my original thoughts.
This post was edited on 3/28/20 at 9:22 pm
Posted on 3/28/20 at 9:55 pm to Little Trump
If I’m healthy and take this drug, what will it do to me? Otherwise, what the frick are we waiting on? So people don’t have the shits for no reason??
Page 2 of 3
Popular
Back to top
Follow TigerDroppings for LSU Football News